Series

Are you Prozempic or Nozempic?

Link in Bio with Jenny and Alejandro
Dr. Rocio Salas goes deep and wide on the use of Ozempic’s for weight loss, explaining the causes of so-called “Ozempic face” and “Ozempic hands.” This far-ranging interview with one of America’s top endocrinologists is a must-see for anyone considering using this and related drugs to manage their weight.
Show transcript
00:00
Ok. So everyone is talking about the new diet drug Ozempic
00:04
which is actually meant it's meant for diabetics technically,
00:07
but people are using it for weight loss.
00:10
and,
00:10
the people that have used it have said that it's been very
00:13
effective and it's helped.
00:15
Have you heard of it?
00:17
Oh, yeah, I've heard of it everywhere.
00:19
I feel like for the last year one of my thea,
00:22
ok, I won't expose them exactly who,
00:25
but the doctor told the nurse the wrong dose and she ended
00:30
up overdosing on OIC,
00:32
her do that apparently.
00:35
Yeah, we've never heard of on the news but it happened
00:37
to my t thank God she's ok now,
00:40
but the dose that they gave her was over 100 times the
00:44
dose it was supposed to be.
00:46
So, yeah, she ended up in urgent care real fast
00:49
and she's all good now.
00:51
But that was her first experience with it and she was,
00:54
she using it for like diabetes or weight loss.
00:57
No, she was doing what she was trying to get snatched
01:01
Yes, I get you.
01:03
And then so, I mean,
01:04
there's a lot of thoughts on the drug and thankfully we have
01:08
a doctor here with us who's very,
01:09
very, very familiar with Ozempic.
01:12
We have Doctor Rocio Salas Whelan to help us understand Ozempic.
01:18
Hi, doctor. Hi doctor.
01:20
Thank you for having me.
01:21
Thanks for being. Yes,
01:22
thank you for coming on.
01:23
So, can you explain how Ozempic works for weight loss?
01:28
So, Ozempic, the drug is Sema tide and they're synthetic
01:34
hormones that we also make in our gut.
01:36
They're called G LP one.
01:38
And the way that they work for type two diabetes,
01:41
they increase insulin production in the pancreas and makes the insulin that
01:45
the patient makes to work better.
01:48
But for weight loss,
01:49
what it does, it increases your satiety hormones when you start
01:53
eating and you're using this medication.
01:54
So basically you get fuller with half a portion or a third
01:59
of a portion of what you normally would need to get full
02:02
And then in between your meals,
02:04
it suppresses your hunger hormones.
02:06
Really. You feel hungry at one point,
02:08
but you eat a small portion and you're physically satisfied and content
02:12
until your next meal.
02:14
And then in the brain,
02:15
we have receptors for these hormones and they take away the reward
02:20
of food or certain beverages or including alcohol,
02:25
right? So let's say somebody who goes for sweets or carbs
02:29
for some sort of relief or anxiety,
02:32
boredom, depression, it just takes it away.
02:36
So there's no drive for that anymore.
02:39
You eat when you're hungry,
02:40
you enjoy it when you're eating,
02:42
but then you get fuller faster and then the food is out
02:45
of your mind. Wow.
02:47
Wow. I never thought about the logistics behind it,
02:52
but that makes sense why you would lose weight.
02:55
You're eating a lot less than what you usually would be eating
02:59
Definitely. So,
03:01
what are the risks or side effects that could occur?
03:04
Always say the benefits or the effectiveness and the safety is going
03:09
to depend on who is giving you the medication.
03:13
How much expertise that physician has on using these drugs.
03:18
Because when they're used by the right person or the right doctor
03:22
they're very minimal side effects.
03:25
Right? Sometimes there's a little bit of nausea and that's just
03:28
what while patients get used to the fullness feeling that they weren't
03:32
used to anymore, but really side effects that will make the
03:37
medication be stopped or like your aunt that need to be taken
03:40
to the hospital or go to urgent care can be prevented if
03:46
who's giving you the medication has expertise on these drugs.
03:50
And, and how long does it take to see weight loss
03:53
result on Ozempic? Really?
03:56
In the first few weeks,
03:57
we can see significant weight loss.
04:00
Now, we're not whenever we're doing weight loss treatment and this
04:03
could be with medications,
04:04
with our medications, we're never looking for a quick,
04:07
rapid weight loss, right?
04:09
Weight loss should be more of a marathon and not a sprint
04:14
And the ideal weight loss is anywhere from 1 to £2
04:17
per week again with medication or without medication because more than that
04:23
the person is losing muscle mass.
04:25
And we don't want that.
04:27
We don't want the person to lose muscle mass because the muscle
04:31
loss is what slows down the metabolism when somebody loses weight.
04:37
That definitely makes sense.
04:38
So recently, I feel like it's been super popular and on
04:42
the news maybe because of celebrities or whatnot.
04:45
But is the drug new or has it been around for a
04:49
while? It is not new and Osmic became the poster child
04:53
of this class of drugs.
04:55
But we have the first FDA approved in its class was in
04:58
2005 by the name of Valera.
05:01
Then it came as Picosa in 2010 and then Osmic in 2017
05:07
And then most recently we have Monro and Zon which is
05:11
Tide and I like to explain them as iphones,
05:14
right? We have the iphone 13 that is Zend and VSA
05:18
We have the iphone 14 which is Osmic and now we
05:21
have the iphone 15 which is Monro and Sepa,
05:24
right? So every generation of them will come safer and we
05:28
see more weight loss on the newer drugs and different drugs.
05:35
So they're they're the same drug.
05:38
But you see like as example,
05:40
Ox OEC is Sema Osmic has the FDA approval for type two
05:45
diabetes, but Sema also named as wo is FDA approved for
05:51
weight loss without diabetes.
05:53
So they're not exclusively type two diabetes drugs.
05:57
Now they are FDA approved for weight loss,
05:59
they just changed the name,
06:01
but it's the same drug,
06:02
same dosing, same pen,
06:04
same effects, but they still call it Ozempic Porque.
06:08
It's the craze one.
06:10
Got it, got it.
06:11
So, for the newest form of Ozempic,
06:14
is that the same form of injection?
06:18
It's a once a week injection and it's tide as the drug
06:23
and that medication definitely we're seeing significant more weight loss and less
06:28
gastric side effects. So almost no nausea compared to older drugs
06:32
also. Who do you think should be taking these drugs for
06:36
weight loss is patients that have a BM I of seven or
06:40
above and one comorbidity from their weight.
06:44
So high blood pressure,
06:45
sleep apnea, joint pain or patients that have a BM I
06:50
equal or greater than 30 we're moving away from the BM I
06:54
slowly but unfortunately, insurance still will make their decision according to
07:00
BM I. So insurance covers these,
07:04
these weight loss. Most commercial insurances Medicare is starting to cover
07:10
with OB and Osem for type two diabetes right now.
07:13
So slowly more insurance are starting to implement them in their plans
07:17
Well, how much is it without insurance?
07:19
It's around $1100 for a month supply or if the person has
07:25
commercial insurance and it's not approved by the insurance,
07:28
there's coupons that the pharmaceuticals have and it comes to about 500
07:33
per month. So half of what out of pocket costs.
07:37
I learned a lot.
07:38
I did too and you explained it so well.
07:41
I love it. I love how you explain everything.
07:44
Thank you. Thank you so much,
07:45
Doctor. We appreciate having you on the show and really giving
07:48
us, you know,
07:49
a breakdown of how Ozempic works and where can we follow you
07:53
Where can people find you?
07:55
Well, on Instagram is at Dr Sala Whelan,
07:58
Drsalas Whelan or also on tiktok.
08:03
It's New York Endocrinology or my web page is NY endocrinology.com.
08:08
Thank you so so much for informing us and having this conversation
08:12
with us today, doctor.
08:13
Thank you. You're very welcome.